The students of English Education Department are being prepared to master the 4C skills; Communication, Creativity, Collaboration, and Critical Thinking skills that are integrated in Public Speaking class. The lecturer of Public Speaking subject conducted activities in teaching Public Speaking that related to the 4C skills. The activities can be found in the teaching and learning process that make the students explore and improve their communication, creativity, collaboration, and critical thinking skills. This research used descriptive qualitative method, and the researcher did observation and interview to collect the data which determined the result of this research. The result is the integration of collaboration skill in teaching Public Speaking has found a bit difficulty, because some activities should have been done in offline meeting. However, the integration of the other skills run well. The lecturer also has conducted the activities that are relatable to the integration of 4C skills in teaching Public Speaking, and provided the activities to the students in learning materials.