The problem of women becoming leaders and gender issues are still often questioned, this is due to the evidence of the Qur'an Surah An-Nisa verse 34 and the hadith of the Prophet Muhammad which hints at the prohibition of women being leaders. Scholars of interpretation have different interpretations of this, here the author will discuss more deeply how Abdullah Yusuf Ali's interpretation of women's leadership is and whether his interpretation contains elements of gender bias. Abdullah Yusuf Ali is a Muslim cleric from India who has a background and knowledge that should be taken into account, especially his contribution to the book of commentary in English. The aim of this research is to find out Abdullah Yusuf Ali's interpretation of women's leadership, as well as whether there is a gender bias in his interpretation. This study uses qualitative methods in analyzing the processed data. In general, Abdullah Yusuf Ali interprets the verse about leadership as not emphasizing or requiring men to be leaders.